METHOD FOR EVALUATING THE CONDITION OF PERIPHERAL BLOOD MONONUCLEAR CELLS IN PULMONARY TUBERCULOSIS PATIENTS Russian patent published in 2019 - IPC G01N33/50 

Abstract RU 2709499 C1

FIELD: medicine.

SUBSTANCE: invention relates to a method for evaluating the state of peripheral blood mononuclear cells, involving determining a phospholipid spectrum of membranes of peripheral blood mononuclear cells. Method is characterized by that evaluation is carried out by determining the relative content of fractions of total lysophospholipids, sphingomyelin and phosphatidylcholine phospholipid spectrum membranes of peripheral blood mononuclear cells and calculating a coefficient determined by formula CC=PC2/SM*LPL, where PC is the relative content of phosphatidylcholine, SM - relative content of sphingomyelin, LPL – relative content of total lysophospholipids; if values of this coefficient are less than or equal to 6.7, reduced functional activity of mononuclear cells is diagnosed.

EFFECT: disclosed is a method of evaluating the condition of peripheral blood mononuclear cells.

1 cl, 3 ex

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RU 2 709 499 C1

Authors

Ryasenskij Sergej Stanislavovich

Ryasenskij Dmitrij Sergeevich

Aseev Aleksandr Vladimirovich

Zubareva Galina Mefodevna

Dates

2019-12-18Published

2019-10-15Filed