METHOD FOR PREDICTION OF LIPID DISTRESS SYNDROME DEVELOPMENT IN PATIENTS WITH STABLE VIROLOGIC RESPONSE TO ANTIVIRAL THERAPY OF CHRONIC HEPATITIS C Russian patent published in 2019 - IPC G01N33/49 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to a method for prediction of developing lipid distress syndrome in patients with stable virological response to an antiviral therapy of chronic viral hepatitis C. Method involves determining a concentration of the following blood values: low-density lipoprotein cholesterol concentration, homocysteine, interleukins 4 and 10 and tumor necrosis factor and subsequent calculation of the value of the discriminant function by formula: DF=347.612x₁+15.403x₂+61.848x₃+3.560x₄+110.687x₅, where DF is the discriminant function value; x₁ is concentration of low-density lipoprotein cholesterol, mmol/l; x₂ is homocysteine concentration, mmol/l; x₃ – concentration of interleukin 4, pg/ml; x₄ – concentration of interleukin 10, pg/ml; x₅ – concentration of tumor necrosis factor, pg/ml; 347.612; 15.403; 61.848; 3.560 and 110.687 – coefficients of the discriminant function, comparing the value of the discriminant function with a constant equal to 3211.09, and the value of the discriminant function more than 3211.09 of the development prediction, and if the discriminant function is less than or equal to 3211.09, predicting the absence of developing lipid distress syndrome for next 10 years of life.

EFFECT: invention provides predicting development of lipid distress syndrome in patients with stable virological response to antiviral therapy of chronic viral hepatitis C, as well as high accuracy of prediction.

1 cl, 2 ex