FIELD: chemistry.
SUBSTANCE: invention relates to biochemistry, in particular to a polynucleotide encoding a stabilized multispecific antibody construct. What is also disclosed is a pharmaceutical composition containing said antibody, an expression vector containing said polynucleotide, a host cell containing said polynucleotide. Disclosed is a method of producing said antibody, as well as use of said antibody or said pharmaceutical composition for treatment.
EFFECT: invention enables to obtain a stabilized multispecific antibody construct.
12 cl, 3 dwg, 6 tbl, 2 ex
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