NEW APPROACH TO TREATING CANCER WITH APPLICATION OF IMMUNOMODULATION Russian patent published in 2020 - IPC A61K45/08 A61K31/69 A61K31/40 A61K31/198 A61K39/395 A61P35/00 A61P37/04 

FIELD: medicine.

SUBSTANCE: group of inventions relates to immuno-oncology, particularly to methods of treating cancer, enhancing the immune response in a subject suffering cancer, as well as treating, slowing or preventing tumour metastases in a cancer patient. That is ensured by administering an effective amount of talabostat or a pharmaceutically acceptable salt thereof in combination with the anti-PD-1 antibody. Also disclosed are methods of treating cancer, enhancing the immune response in a subject suffering cancer, as well as treating, slowing down or preventing tumour metastasis in a cancer patient. That is ensured by administering an effective amount of talabostat or a pharmaceutically acceptable salt thereof in combination with the anti-CTLA4 antibody.

EFFECT: group of inventions provides a synergetic effect when combining talabostat with the anti-PD-1 antibody.

195 cl, 9 dwg, 8 tbl, 1 ex