USE OF EP4 RECEPTOR ANTAGONISTS FOR TREATMENT OF NASH-ASSOCIATED LIVER CANCER Russian patent published in 2021 - IPC A61K31/437 A61K31/64 A61P35/00 A61P1/16 C07D471/04 

Abstract RU 2762193 C2

FIELD: medicine.

SUBSTANCE: invention relates to a method for the treatment of NASH-associated liver cancer, which includes the administration of pharmaceutically effective amount of 3-[2-(4-{2-ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridine-1-yl}phenyl)ethyl]-1-[(4-methylbenzene)sulfonyl]urea (compound C) or its pharmaceutically acceptable salt to a person or animal in need of it.

EFFECT: new method is developed for the treatment of NASH-associated liver cancer by means of prostaglandin E2 receptor 4 (EP4) antagonist, which is a compound C, which can be used in medicine.

4 cl, 8 dwg, 6 ex

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RU 2 762 193 C2

Authors

Ohtani, Naoko

Kamachi, Fumitaka

Loo, Tze Mun

Koizumi, Shinichi

Okumura, Takako

Dates

2021-12-16Published

2017-11-02Filed