FIELD: medicine; pharmaceuticals.
SUBSTANCE: group of inventions relates to oncology and pharmacy. Disclosed are a method of treating associated non-alcoholic steatohepatitis (NASH-associated) liver cancer involving administering a pharmaceutically effective amount of 4-[(1S)-1-({[5-chloro-2-(3-fluorophenoxy)pyridin-3-yl]carbonyl}amino)ethyl]benzoic acid or its salts (embodiments), use of said compound or salt thereof for treating NASH-associated liver cancer and use thereof for producing a medicament for the same purpose.
EFFECT: technical result: compound (or its salt) inhibits the development of obesity-related NASH-associated liver cancer, while re-activating anti-tumour immunity in the microenvironment of the cancer, in particular reduces the population of immune suppressing cells Treg (Foxp3+) in tumour tissue.
12 cl, 8 dwg, 6 ex
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Authors
Dates
2020-03-23—Published
2017-11-02—Filed