FIELD: biochemistry.
SUBSTANCE: group of inventions relates to a microorganism of the genus Saccharomyces, having the ability to produce lactic acid in comparison with an unmodified microorganism, and to a method of producing lactic acid using it. Microorganism of Saccharomyces genus is modified so that pyruvate decarboxylase (PDC) activity is inactivated in comparison with its endogenous activity, ATP-citrate lyase (ACL) activity is introduced, and pyruvate biosynthesis path is intensified compared to endogenous biosynthesis. Method of producing lactic acid involves culturing said microorganism of the genus Saccharomyces in a medium and recovering lactic acid from the cultured microorganism or from the medium.
EFFECT: group of inventions increases the amount of lactic acid produced.
12 cl, 2 dwg, 13 tbl, 10 ex
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Year |
Author |
Number |
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|
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|
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2020 |
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|
RU2802274C1 |
| POLYPEPTIDE HAVING D-LACTATE DEHYDROGENASE ACTIVITY, POLYNUCLEOTIDE ENCODING POLYPEPTIDE, AND PROCESS FOR PRODUCTION OF D-LACTIC ACID |
2010 |
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|
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2008 |
- Khogsett Dehvid A
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|
RU2541785C2 |
| DIAMINE-PRODUCING MICROORGANISM AND METHOD FOR PRODUCING DIAMINE USING SAME |
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|
RU2672323C2 |
| RECOMBINANT MICROORGANISM WITH INCREASED ABILITY TO PRODUCE PUTRESCINE, AND METHOD OF PRODUCING PUTRESCINE USING SAID MICROORGANISM |
2013 |
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|
RU2604806C2 |
