NEW VARIANT OF BRANCHED-CHAIN AMINO ACID AMINOTRANSFERASE AND A METHOD OF PRODUCING LEUCINE USING IT Russian patent published in 2023 - IPC C12N9/10 C12P13/06 

Abstract RU 2802274 C1

FIELD: biotechnology.

SUBSTANCE: invention is a polypeptide involved in the production of L-leucine, in which the amino acid valine (V) is at position 156 from the N-terminus of the amino acid sequence of SEQ ID NO: 1 is replaced by another amino acid. The invention also relates to a polypeptide involved in the production of L-leucine, in which the amino acid valine (V) at position 156 from the N-terminus of the amino acid sequence having 90% or greater homology or identity with the amino acid sequence of SEQ ID NO: 1 is replaced by another amino acid. The invention also relates to a method of producing leucine, which includes cultivating a microorganism transformed with a vector containing a polypeptide according to the invention.

EFFECT: obtaining L-lysine with a high degree of efficiency.

11 cl, 3 tbl, 3 ex

Similar patents RU2802274C1

Title Year Author Number
VERSION OF ISOPROPYL MALATE SYNTHASE AND METHOD OF PRODUCING L-LEUCINE USING SAME 2022
  • Lee Hayun
  • Kim Ju Eun
  • Lee Ji Hye
RU2824530C1
VARIANT OF ALDOLASE AROG AND METHOD OF PRODUCING BRANCHED-CHAIN AMINO ACID USING SAME 2021
  • Lee Hayun
  • Kim Ju Eun
  • Lee Ji Hye
  • Lee Heeseok
  • Kim Kyungrim
RU2826456C1
NEW POLYPEPTIDE AND METHOD OF PRODUCING L-LEUCINE USING ITS 2021
  • Lee Hayun
  • Kim Ju Eun
  • Shim Jihyun
  • Lee Ji Hye
  • Lee Sung Gun
RU2811433C1
NEW MODIFIED POLYPEPTIDE WITH REDUCED CITRATE SYNTHASE ACTIVITY AND METHOD FOR PRODUCING L-AMINO ACID USING IT 2020
  • Ahn Chan Hong
  • Kim Ju Eun
  • Bae Hyun-Jung
  • Lee Imsang
  • Lee Ji Hye
  • Lee Hayun
RU2805253C1
VARIANT OF PHOSPHORIBOSYL PYROPHOSPHATE AMIDOTRANSFERASE AND METHOD OF PRODUCING PURINE NUCLEOTIDE USING IT 2019
  • Lee Ji Hye
  • Park So-Jung
  • Baek Min Ji
RU2736372C1
MICROORGANISM OF THE GENUS CORYNEBACTERIUM, HAVING L-ISOLEUCINE-PRODUCING CAPACITY, AND A METHOD OF PRODUCING L-ISOLEUCINE USING SAID MICROORGANISM 2016
  • Kwon Su Yon
  • Jang Jae Woo
  • Kim Min Se
  • Kim Ju Jeong
RU2698394C1
VARIANT OF INNER MEMBRANE PROTEIN AND METHOD FOR OBTAINING TARGET PRODUCT USING IT 2020
  • Kim Seo Yun
  • Cho Seung Hyun
  • Lee Jae Min
  • Baek Min Ji
RU2804941C1
NEW ADENYL-SUCCINATE SYNTHETASE AND METHOD FOR PRODUCING PURINE NUCLEOTIDES USING IT 2018
  • Baek Min Ji
  • Lee Ji Hye
  • Park So-Jung
  • Bae Jee Yeon
RU2770464C1
NOVEL POLYPEPTIDE AND A METHOD FOR PRODUCING IMP USING SAID POLYPEPTIDE 2019
  • Rho Jin Ah
  • Yoon Byoung Hoon
  • Park So-Jung
  • Baek Min Ji
  • Lee Ji Hye
RU2733422C1
MODIFIED HOMOSERINE DEHYDROGENASE AND METHOD FOR PRODUCING HOMOSERINE OR L-AMINO ACID OF HOMOSERINE ORIGIN USING SUCH HOMOSERINE DEHYDROGENASE 2019
  • Kim Hyo Jin
  • Huh Lan
  • Lim Sang Jo
  • Kim Hyun Ah
  • Kim Hyoung Joon
  • Seo Chang Il
  • Lee Seung Bin
  • Lee Ji Sun
RU2733426C1

RU 2 802 274 C1

Authors

Bae Hyun-Jung

Kim Ju Eun

Baek Min Ji

Lee Ji Hye

Dates

2023-08-24Published

2020-11-24Filed