FIELD: medicine.
SUBSTANCE: proposed group of inventions relates to medicine. Disclosed is a pharmaceutical composition for preventing and treating the eye disease caused by neovascularisation, containing a fusion protein in which the tissue penetrating peptide is fused with anti-VEGF. Disclosed method obtaining a fused protein, use thereof to produce a therapeutic agent for eyeball-induced eye diseases and a method of treating such a disease.
EFFECT: disclosed group of inventions provides effective treatment caused by neovascularisation of eye disease.
11 cl, 13 dwg, 7 tbl, 8 ex
| Title | Year | Author | Number |
|---|---|---|---|
| PHARMACEUTICAL COMPOSITION CONTAINING AS AN ACTIVE INGREDIENT A FUSED PROTEIN IN WHICH A TUMOR-PENETRATING PEPTIDE AND AN ANTIANGIOGENIC AGENT ARE FUSED FOR PREVENTING AND TREATING CANCER OR ANGIOGENESIS-RELATED DISEASES | 2016 |
|
RU2727238C2 |
| Fab FRAGMENT OF HUMANIZED ANTIBODY AGAINST VEGF AND ITS USE | 2020 |
|
RU2802960C2 |
| PROTEIN COMPOSITIONS AGAINST VEGF AND METHODS FOR THEIR PRODUCTION | 2020 |
|
RU2795973C1 |
| ATRIAL NATRIURETIC PEPTIDE GRAFTED ANTIBODIES | 2019 |
|
RU2822433C2 |
| PROTEIN COMPOSITIONS AGAINST VEGF AND METHODS FOR THEIR PRODUCTION | 2020 |
|
RU2785994C1 |
| PROTEIN COMPOSITIONS AGAINST VEGF AND METHODS FOR THEIR PRODUCTION | 2020 |
|
RU2778325C1 |
| PROTEIN COMPOSITIONS AGAINST VEGF AND METHODS FOR THEIR PREPARATION | 2020 |
|
RU2788949C1 |
| ANTI-CEACAM6 ANTIBODIES AND USE THEREOF | 2016 |
|
RU2739163C2 |
| POLYFUNCTIONAL PROTEIN MOLECULES CONTAINING DECORIN AND USE THEREOF | 2019 |
|
RU2823357C2 |
| CHIMERIC CYTOKINE RECEPTOR | 2016 |
|
RU2826122C1 |
