FIELD: biotechnology; biomedicine.
SUBSTANCE: invention relates to polyfunctional protein molecules containing decorin, and their applications. In particular, the present invention relates to polyfunctional protein molecules containing decorin and a targeting polypeptide, such as an antibody, as well as methods for preparing them and using them.
EFFECT: invention provides novel therapeutic agents which target VEGF or immune checkpoints.
22 cl, 7 dwg, 4 tbl, 3 ex
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| MOLECULES TARGETING A TYPE III SECRETION SYSTEM | 2016 |
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RU2759949C2 |
| POLYVALENT AND POLYSPECIFIC OX40-BINDING FUSED PROTEINS | 2017 |
|
RU2773052C2 |
| BISPECIFIC PROTEIN | 2019 |
|
RU2784486C1 |
