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2 712 761

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C1

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IPC

A61K38/22(2006-01-01)

A61P11/00(2006-01-01)

A61P3/10(2006-01-01)

(21) (22)

Application

2019120915, 2019-07-02

(24)

Start date

2019-07-02

(22)

Actual filing date

2019-07-02

(45)

Published

2020-01-31

(72)

Inventor

Skurikhin Evgenij GermanovichPershina Olga ViktorovnaPakhomova Angelina VladimirovnaErmakova Nataliya NikolaevnaKrupin Vyacheslav AndreevichPan Edgar SergeevichDygaj Aleksandr Mikhajlovich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Nauchnoe Uchrezhdenie Natsionalnyj Issledovatelskij Meditsinskij Tsentr Rossijskoj Akademii Nauk" Nimts)

AGENT FOR PULMONARY ENDOTHELIAL REGENERATION STIMULATION AT METABOLIC SYNDROME COMBINED WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE Russian patent published in 2020 - IPC A61K38/22 A61P11/00 A61P3/10 

Abstract RU 2712761 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine. Disclosed is the use of glucagon-like peptide 1 (GLP-1) for stimulating pulmonary endothelial regeneration in a combined pathology of metabolic syndrome and chronic obstructive pulmonary disease.

EFFECT: technical result consists in the implementation of the prescription, wherein the introduction of GLP-1 to the mice with the above pathology resulted in a significant increase in endothelial progenitor cells in the lungs, comparable to their number in the intact animals.

1 cl, 3 dwg, 10 tbl

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RU 2 712 761 C1

Authors

Skurikhin Evgenij Germanovich

Pershina Olga Viktorovna

Pakhomova Angelina Vladimirovna

Ermakova Nataliya Nikolaevna

Krupin Vyacheslav Andreevich

Pan Edgar Sergeevich

Dygaj Aleksandr Mikhajlovich

Dates

2020-01-31—Published

2019-07-02—Filed

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