SUBSTRATES OF MATRIX METALLOPROTEINASE AND OTHER CLEAVABLE MOIETIES AND METHODS FOR USE THEREOF Russian patent published in 2020 - IPC A61K39/395 A61P35/00 

Abstract RU 2715232 C2

FIELD: medicine.

SUBSTANCE: invention refers to medicine and concerns an isolated polypeptide containing a cleavable moiety (CM) containing an amino acid sequence selected from a group consisting of SEQ ID NO: 459–469 and 31, where the cleaved fragment is a substrate for a matrix metalloprotease.

EFFECT: invention provides cleavage of the recovered polypeptide by matrix metalloprotease.

15 cl, 7 dwg, 10 tbl, 14 ex

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RU 2 715 232 C2

Authors

Mur, Stefen, Dzhejms

Nguen, Margaret, Tkhi Luu

Khostetter, Deniel, R.

Vasileva, Olga

Flandes, Zhan, Grejs

Dates

2020-02-26Published

2014-09-25Filed