FIELD: chemistry.
SUBSTANCE: invention relates to biochemistry, particularly to an antibody which specifically binds to PD-1. Also disclosed is a composition comprising said antibody, a nucleic acid encoding said antibody, a vector and a host cell containing said nucleic acid. Disclosed are methods of treating cancer and infectious disease, diagnosing, selecting, detecting, amplifying using said antibody, a method for producing said antibody, a method of reproducing a population of T-cells and using said antibody for preparing a drug for detecting PD-1.
EFFECT: invention provides effective treatment of diseases associated with PD-1.
21 cl, 24 dwg, 1 tbl, 1 ex
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Authors
Dates
2020-03-02—Published
2015-10-27—Filed