FIELD: chemistry.
SUBSTANCE: invention relates to crystalline monohydrate of clozapine of formula (I), in particular to its polymorphs 1 and 2, methods for preparing them and pharmaceutical compositions based thereon.
EFFECT: technical result is obtaining novel polymorphs of crystalline monohydrates of formula (I), having lower toxicity compared to clozapine.
6 cl, 6 dwg, 1 tbl, 2 ex
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