FIELD: chemistry.
SUBSTANCE: invention relates to a salt of 4-methylbenzenesulfonic acid and 2,2-dimethyl-6-((4-((3,4,5-trimethoxyphenyl)amino)-1,3,5-triazin-2-yl)amino)-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one base, its hydrate, solvate or polymorph salt, hydrate or solvate modification effective to inhibit Src 
kinases. The invention also relates salt application for prevention and/or treatment of a disorder associated with aberrant kinase activity, and a pharmaceutical composition.
EFFECT: new salt can be used to prevent or treat a disorder associated with aberrant kinase activity.
16 cl, 21 dwg, 11 tbl, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
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| NOVEL CRYSTALLINE SALT FORM 3-(1,2,4-TRIAZOLO[4,3-A]PYRIDIN-3-YLETHYNYL)-4-METHYL-N-(4-((4-METHYLPIPERAZIN-1-YL)METHYL)-3-TRIFLUOROMETHYLPHENYL) BENZAMIDE FOR MEDICAL APPLICATION | 2016 |
|
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| CHEMICAL COMPOUNDS AS INTERLEUKIN-1 INHIBITORS | 2018 |
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| METHODS AND COMPOSITIONS FOR GROWTH STIMULATION OF NEURITIS | 1996 |
|
RU2197240C2 |
