DERIVATIVES OF 5H-DIBENZO[b, e][1, 4]DIAZEPINE AND ITS APPLICATION Russian patent published in 2012 - IPC C07D403/04 C07D223/20 A61K31/5517 A61P25/18 

Abstract RU 2441867 C2

FIELD: pharmacology.

SUBSTANCE: invention refers to the area of chemistry, chemical and pharmaceutical industry and medicine and refers to compounds of formula (1) that can be useful as antipsychotic drugs. Described compounds of formula (1) are the derivatives of 5H-dibenzo[b, e][1, 4]diazepine or its pharmacologically acceptable salts with acid and application of the compounds. Compounds of formula (1) possess higher activity compared to clozapine.

EFFECT: improved antipsychotic effect.

8 cl, 23 ex, 2 tbl

Similar patents RU2441867C2

Title Year Author Number
AMINOSUBSTITUTED DIARYL [a, d] CYCLOHEPTANE ANALOGUES AS MUSCARINIC AGONISTS AND METHOD OF TREATING PSYCHONEUROLOGICAL DISORDERS 2004
  • Ehk Fredrik
  • Ol'Sson Rodzher
  • Ol'Sson Jergen
RU2394030C2
SUBSTITUTED [1,2,4]TRIAZOLO[1,5-A]PYRIMIDINE-7-YL COMPOUNDS AS THE INHIBITORS OF PDE2 2015
  • Brajtenbukher Dzhejms
  • Fristoun Gremi
  • Gomez Loran
  • Lemus Robert
  • Li Kiv
  • Makkarrik Margaret
  • Verner Uilyam
  • Vikers Troj
RU2659070C9
DERIVATIVES OF DIARYLALKANES CONTAINING ALICYCLIC GROUP AND ELICITING ANTAGONISM WITH RESPECT TO SEROTONIN-2-RECEPTORS AND/OR INHIBITORY ACTIVITY WITH RESPECT TO SQUALENE SYNTHASE, COMPOSITION FOR TREATMENT AND PROPHYLAXIS OF CARDIOVASCULAR DISEASES 1997
  • Koiti Fudzimoto
  • Naoki Tanaka
  • Fumitosi Asaj
  • Taketosi Ogava
  • Tejitiro Koga
  • Tatsuo Tanimoto
  • Esio Tsudzita
  • Khirojuki Kojke
RU2139277C1
SUBSTITUTED COMPOUNDS OF THIOPHEN AND FURAN-CONDENSED AZOLOPYRIMIDIN-5-(6H)-OH 2013
  • Brajtenbukher Dzhejms
  • Branstetter Brajan
  • Dik Brajan
  • Gomez Loran
  • Khadson Endryu Richard
  • Merron Temi Dzho
  • Vikers Troj
  • Piters Marko
RU2659779C2
α, ω-DIARYL ALKANES AND METHOD FOR THEIR PRODUCTION 1993
  • Kojti Fudzimoto[Jp]
  • Naoki Tanaka[Jp]
  • Fumitosi Asaj[Jp]
  • Tomijosi Ito[Jp]
  • Khirojuki Kojke[Jp]
RU2105752C1
PYRAZOLE DERIVATIVES APPLIED AS PROTEIN KINASE INHIBITORS 2013
  • Khollik Dzhonatan Dzhejms
  • Dzhouns Styuart Donald
  • Flinn Kler Dzhun
  • Tomas Majkl Dzhordzh
RU2623221C2
BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS 2016
  • Shook Brian C.
  • Kim In Jong
  • Blaisdell Thomas P.
  • Yu Jianming
  • Panarese Joseph
  • Or Yat Sun
RU2738232C2
BICYCLIC KETONES AND METHODS OF THEIR USE 2018
  • Patel, Snakhel
  • Gamilton, Gregori
  • Chzhao, Gujlin
  • Chen, Khuejfen
  • Daniels, Blejk
  • Stivala, Krejg
RU2797922C2
BICYCLIC HETEROCYCLIC COMPOUNDS AND THEIR APPLICATIONS 2020
  • Kregg, Dzhejms Dzhozef
  • Bakl, Andreas
  • Aaj, Naing
  • Tambo-Ong, Arlin A.
  • Koltun, Elena S.
  • Dzhill, Edrian Liam
  • Tompson, Severin
  • Glidt, Mika Dzh.
RU2811612C2
NOVEL BENZODIOXOLS 2003
  • Alanen Aleksander
  • Belajkher Konrad
  • Guba Vol'Fgang
  • Khap Vol'Fgang
  • K'Juber Dagmar
  • Ljubbers Tomas
  • Planshe Zhan-Mark
  • Rozher-Ehvan Mark
  • Shnajder Gisbert
  • Tsjugge Jokhen
  • Roshe Oliv'E
RU2304580C2

RU 2 441 867 C2

Authors

Morozova Margarita Alekseevna

Beniashvili Allan Gerovich

Nesteruk Vladimir Viktorovich

Zapol'Skij Maksim Ehduardovich

Dates

2012-02-10Published

2010-05-13Filed