DEUTERATED THIENOPIPERIDINE DERIVATIVES, METHOD FOR PRODUCTION THEREOF AND USE THEREOF Russian patent published in 2020 - IPC C07D495/04 A61K31/4535 A61K31/675 A61P9/10 A61P7/02 A61P9/04 C07F9/6561 

Abstract RU 2716141 C2

FIELD: chemistry.

SUBSTANCE: invention relates to deuterated derivatives of thienopiperidine with a structure of formula (I) or pharmaceutically acceptable salts thereof

Formula (I),

where X is P or S; m equals 0 or 1; n equals 0 or 1; R1 is selected from hydrogen, linear or branched C1-C4alkyl substituted or unsubstituted with halogen or phenyl; R2 is not substituted or is selected from hydrogen, linear or branched C1-C4alkyl, substituted or unsubstituted with halogen or phenyl, wherein if R2 is not substituted, then X and O form a double bond, as well as a method for production and use thereof for treating and preventing cardiovascular and cerebrovascular diseases.

EFFECT: treatment and prevention of cardiovascular and cerebrovascular diseases.

9 cl, 2 dwg, 4 tbl, 12 ex

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RU 2 716 141 C2

Authors

Wang, Guocheng

Zhong, Jun

Xu, Xueyu

Dates

2020-03-06Published

2016-06-21Filed