FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to experimental biology and pharmacology, and can be used for preventing rhabdomyolysis-induced renal injury. An experimental animal is intramuscularly injected with 50 % glycerol in dose of 0.8 ml/100 g of body weight. From the following day after experimental renal injury is reproduced for 30 days, acizole in dose of 30 mg/kg is administered intragastrically daily to animals.
EFFECT: method provides studying the preventive effect of acizole on restoring renal function on the background of toxic nephropathy caused by rhabdomyolysis, due to the fact that from the following day after experimental renal damage within 30 days, acizole is administered.
1 cl, 2 tbl, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PREVENTION OF NEPHROTOXIC ACTION OF ANTIMONY IN RATS IN EXPERIMENT | 2023 |
|
RU2815874C1 |
| METHOD OF PREVENTING TOXIC LEAD EFFECT ON EXPERIMENT ANIMALS WITH CHRONIC POISONING | 2008 |
|
RU2358328C1 |
| METHOD FOR THE PREVENTION OF ALCOHOL-INDUCED NEPHROPATHY ON THE BACKGROUND OF LEAD INTOXICATION IN RATS IN THE EXPERIMENT | 2022 |
|
RU2786469C1 |
| METHOD FOR PREVENTION OF TOXIC ACTION OF COBALT IN EXPERIMENTAL ANIMALS SUFFERING CHRONIC POISONING | 2010 |
|
RU2431482C1 |
| METHOD OF CADMIUM NEPHROPATHY PREVENTION IN EXPERIMENTAL ANIMALS SUFFERING FROM CHRONIC POISONING | 2008 |
|
RU2366459C1 |
| METHOD FOR PREVENTION OF TOXIC ACTION OF CADMIUM IN EXPERIMENTAL ANIMALS SUFFERING CHRONIC POISONING | 2011 |
|
RU2462764C1 |
| METHOD FOR PREVENTION OF TOXIC ACTION OF CADMIUM IN EXPERIMENTAL ANIMALS SUFFERING CHRONIC POISONING | 2011 |
|
RU2461894C1 |
| METHOD FOR PREVENTION OF NEPHROTOXIC EFFECT OF MOLYBDENUM | 2020 |
|
RU2786641C2 |
| METHOD OF REDUCING NEPHROTOXICITY OF AMMONIUM MOLYBDATE | 2015 |
|
RU2588319C1 |
| METHOD OF CHRONIC TOXIC NEPHROPATHY MODELING | 2008 |
|
RU2358327C1 |
