FIELD: technological processes.
SUBSTANCE: group of inventions relates to methods of producing intermediate compounds used for synthesis of everolimus, and methods for producing everolimus. Disclosed is a method of producing an everolimus precursor of rapamycin and an organosilicon compound in the presence of a saturated nitrogen-containing heterocycle, a version thereof and corresponding versions of subsequent production of everolimus.
EFFECT: disclosed methods of producing intermediate compounds and subsequent production thereof of everolimus enable to increase output and purity of the end product, as well as reduce the amount of production wastes.
103 cl, 2 tbl, 7 ex
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