FIELD: medicine; pharmaceuticals.
SUBSTANCE: method of inducing satiety in a subject in need thereof, a method for prolonging satiety in a subject in need thereof, a method for reducing food intake in a subject in need thereof, a method for reducing weight gain in a subject in need thereof, a method of stimulating weight loss in a subject in need thereof subject. Inventions provide for the oral administration of an effective amount of a bacterium expressing a ClpB protein which contains the ARWTGIPVSR sequence to the said individual.
EFFECT: inventions enable to cause satiety, prolong satiety, reduce food intake, control weight gain and/or stimulate body weight reduction in a subject.
44 cl, 1 dwg, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
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|
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| LYSINE POLYPEPTIDES ACTIVE AGAINST GRAM-NEGATIVE BACTERIA | 2016 |
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| TREATMENT OF ABNORMAL VISCERAL FAT DEPOSITION WITH FIBROBLAST GROWTH FACTOR 3 (sFGFR3) SOLUBLE POLYPEPTIDES | 2018 |
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| MODIFIED GRAM-POSITIVE BACTERIA AND THEIR APPLICATIONS | 2012 |
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| RECOMBINANT YEAST CELLS PRODUCING POLYLACTIC ACID AND THEIR USE | 2016 |
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RU2782529C1 |
