FIELD: chemistry.
SUBSTANCE: invention relates to organic chemistry, to novel biologically active substances of class of complex compounds of N-hetarylamides of 4-(het)aryl-2-hydroxy-4-oxobut-2-enoic acids, specifically to a compound of tris{[1-(6-methylbenzo[d]thiazol-2-yl)amino-1,4-dioxo-4-(p-tolyl)but-2-en-2-yl]oxy}iron formula 1
.
EFFECT: disclosed compound has high anti-inflammatory action, as well as low acute toxicity and can be used as an anti-inflammatory agent.
1 cl, 1 tbl, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| 2-HYDROXY-N-(6-METHOXYBENZO[D]THIAZOL-2-YL)-4-OXO-4-PHENYLBUT-2-ENAMIDE, HAVING GASTROPROTECTIVE AND IMMUNOMODULATORY ACTION | 2018 |
|
RU2723897C2 |
| 3-BROMO-4-(4-METHOXYPHENYL)-N-(5-METHYL-1,3,4-THIADIAZOL-2-YL)-2,4-DIOXOBUTANAMIDE, HAVING ANTIMICROBIAL ACTION | 2018 |
|
RU2717243C2 |
| 2-HYDROXY-4-OXO-4-(4-CHLOROPHENYL)-2-BUTENOATE 2-[(6-ETHOXY)BENZO[D]-THIAZOLYL]AMMONIUM WITH ANTHELMINTIC AND INSECTICIDAL ACTIVITY | 2016 |
|
RU2657246C2 |
| 2-{[2-(ADAMANTAN-1-YL)-2-OXOETHYLIDENEHYDRAZINYL-4-(Β-NAPHTHALYL)-4-OXOBUT-2-ENOYL]THIO} SODIUM ETHANOATE WITH WOUND HEALING AND ANTI-INFLAMMATORY ACTIVITY | 2023 |
|
RU2808431C1 |
| 4-ARYL-2-HYDROXY-4-OXO-3-(2-OXO-3,4-DIHYDRO-2H-1,4-BENZOXAZINYL)-2-BUTENOIC ACID TRIAZYLAMIDES ELICITING ANTI-INFLAMMATORY ACTIVITY | 2001 |
|
RU2199537C1 |
| N-(1-H-BENZO[d]IMIDAZOLE-2-yl)-2-(2-(DIPHENYLMETHYLENE)HYDRAZINYL)-5,5-DIMETHYL-4-OXOHEX-2-ENEAMIDE EXHIBITING ANALGESIC ACTIVITY | 2021 |
|
RU2786673C1 |
| N-(2-BENZOTHIAZOLYL)AMIDE 2-HYDROXY-4-OXO-4-(4-CHLOROPHENYL)-2-BUTENOIC ACID HAVING ANTIMICROBIAL AND ANTI-INFLAMMATORY ACTIVITY | 2008 |
|
RU2396262C2 |
| APPLICATION OF METHYL 5-BENZOYL-6-(4-FLUOROPHENYL)-4-METHOXY-2-THIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLATE AS AN ANTI-INFLAMMATORY AGENT | 2022 |
|
RU2786805C1 |
| 4-(4-METHOXYPHENYL)-2-{2-[2-OXO-(3-CHLORO-ADAMANTAN-1-YL)-ETHYLIDENE]HYDRAZINYL}-4-OXOBUT-2-ENOATE SODIUM WITH HEMOSTATIC ACTIVITY | 2016 |
|
RU2663624C1 |
| FURAN-2-YLMETHYL-2-(2-(DIPHENYLMETHYLENE)HYDRAZINYL)-5,5-DIMETHYL-4-OXOHEX-2-ENOATE WITH ANALGESIC AND ANTI-INFLAMMATORY ACTIVITY | 2021 |
|
RU2784447C2 |
