FIELD: organic chemistry.
SUBSTANCE: invention relates to novel biologically active substances of class N-hetarylamides of 4-(het)aryl-2-hydroxy-4-oxobut-2-enoic acids, specifically to 2-hydroxy-N-(6-methoxybenzo[d]thiazol-2-yl)-4-oxo-4-phenylbut-2-enamide of formula (1), having gastroprotective and immunomodulatory action.
.
EFFECT: technical result is compound of 2-hydroxy-N-(6-methoxybenzo[d]thiazol-2-yl)-4-oxo-4-phenylbut-2-enamide, having high gastroprotective and immunomodulatory action, as well as low acute toxicity.
1 cl, 2 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| TRIS {[1-(6-METHYLBENZO[D]THIAZOL-2-YL)AMINO-1,4-DIOXO-4-(P-TOLYL) BUT-2-EN-2-YL]OXY} IRON HAVING ANTI-INFLAMMATORY ACTION | 2018 |
|
RU2717242C2 |
| 2-HYDROXY-4-OXO-4-(4-CHLOROPHENYL)-2-BUTENOATE 2-[(6-ETHOXY)BENZO[D]-THIAZOLYL]AMMONIUM WITH ANTHELMINTIC AND INSECTICIDAL ACTIVITY | 2016 |
|
RU2657246C2 |
| 3-BROMO-4-(4-METHOXYPHENYL)-N-(5-METHYL-1,3,4-THIADIAZOL-2-YL)-2,4-DIOXOBUTANAMIDE, HAVING ANTIMICROBIAL ACTION | 2018 |
|
RU2717243C2 |
| 4-(4-METHOXYPHENYL)-2-{2-[2-OXO-(3-CHLORO-ADAMANTAN-1-YL)-ETHYLIDENE]HYDRAZINYL}-4-OXOBUT-2-ENOATE SODIUM WITH HEMOSTATIC ACTIVITY | 2016 |
|
RU2663624C1 |
| ETHYL 4-(5-BENZOYL-6-(4-(DIETHYLAMINO)PHENYL)-4-HYDROXY-2-THIOXOHEXAHYDROPYRIMIDIN-4-CARBOXAMINO)BENZOATE, EXHIBITING ANALGESIC AND ANTI-INFLAMMATORY ACTION | 2019 |
|
RU2717246C1 |
| 2-{[2-(ADAMANTAN-1-YL)-2-OXOETHYLIDENEHYDRAZINYL-4-(Β-NAPHTHALYL)-4-OXOBUT-2-ENOYL]THIO} SODIUM ETHANOATE WITH WOUND HEALING AND ANTI-INFLAMMATORY ACTIVITY | 2023 |
|
RU2808431C1 |
| 2-HYDROXY-4-METHYLPHENYL-4-OXO-2-BUTENOATE OF THIAZONYL AMMONIUM, POSSESSING HYPOGLYCEMIC AND NOOTROPIC ACTIVITY | 2011 |
|
RU2512291C2 |
| BIS{3-(4-METHYLPHENYL)-1-N2-[2-(ADAMANTAN-1-YL)-2-OXO-ETHYLIDENE HYDRAZIDO]-1,3-PROPANEDIONATO}NICKEL HAVING ANTIMICROBIAL ACTIVITY | 2016 |
|
RU2670200C2 |
| 2-(4-METHOXYPHENYLAMINO)-4-(2,4-DIMETHYLPHENYL)-1-(PIPERAZIN-1-YL)BUT-2-ENE-1,4-DIONE HYDROCHLORIDE WITH HEMOSTATIC ACTIVITY | 2016 |
|
RU2679450C2 |
| N-(2-THIAZOLYL)AMIDE OF 2-(2-OXO-3-INDOLINYLIDENE)HYDRAZINO-4-OXO-4-PHENYL-2-BUTENOIC ACID HAVING ANTIBACTERIAL AND ANALGESIC ACTIVITY | 2008 |
|
RU2401837C2 |
