FIELD: organic chemistry; pharmaceuticals.
SUBSTANCE: invention relates to a biologically active substance of class 2-hydrazinyl derivatives of 4-aryl-4-oxobutanoic acids. The following is disclosed: 2-{[2-(adamantan-1-yl)-2-oxoethylidenehydrazinyl-4-(β-naphthalyl)-4-oxobut-2-enoyl]thio}sodium ethanoate of formula 1, which has wound-healing and anti-inflammatory activity.
EFFECT: invention provides effective anti-inflammatory and wound-healing effects with low toxicity.
1 cl, 1 tbl, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| 4-(4-METHOXYPHENYL)-2-{2-[2-OXO-(3-CHLORO-ADAMANTAN-1-YL)-ETHYLIDENE]HYDRAZINYL}-4-OXOBUT-2-ENOATE SODIUM WITH HEMOSTATIC ACTIVITY | 2016 |
|
RU2663624C1 |
| BIS{3-(4-METHYLPHENYL)-1-N2-[2-(ADAMANTAN-1-YL)-2-OXO-ETHYLIDENE HYDRAZIDO]-1,3-PROPANEDIONATO}NICKEL HAVING ANTIMICROBIAL ACTIVITY | 2016 |
|
RU2670200C2 |
| TRIS {[1-(6-METHYLBENZO[D]THIAZOL-2-YL)AMINO-1,4-DIOXO-4-(P-TOLYL) BUT-2-EN-2-YL]OXY} IRON HAVING ANTI-INFLAMMATORY ACTION | 2018 |
|
RU2717242C2 |
| N-[4-(4-BROMOPHENYL)-2-HYDROXY-4-OXOBUT-2-ENOYL]-2-HYDROXYBENZOHYDRAZIDE, HAVING ANTIFUNGAL ACTIVITY | 2024 |
|
RU2840395C1 |
| 2-HYDROXY-N-(6-METHOXYBENZO[D]THIAZOL-2-YL)-4-OXO-4-PHENYLBUT-2-ENAMIDE, HAVING GASTROPROTECTIVE AND IMMUNOMODULATORY ACTION | 2018 |
|
RU2723897C2 |
| 2-(1,2-DIPHENYL-2-OXOETHYLIDENEHYDRAZINO)-4-(4-METHOXYPHENYL)-4-OXOBUT-2-ENE ACID WITH ANTI-INFLAMMATORY AND ANALGESIC EFFECT | 2006 |
|
RU2348613C2 |
| 3-BROMO-4-(4-METHOXYPHENYL)-N-(5-METHYL-1,3,4-THIADIAZOL-2-YL)-2,4-DIOXOBUTANAMIDE, HAVING ANTIMICROBIAL ACTION | 2018 |
|
RU2717243C2 |
| 2-[2-(3-CHLORO-ADAMANTAN-1-YL)-2-OXOETHYLIDENEHYDRAZINO]-4-(2,4-DIMETHOXYPHENYL)-4-OXO-2-BUTENOIC ACID HAVING ANTI-FLAVIVIRAL ACTIVITY | 2015 |
|
RU2655609C2 |
| 2-HYDROXY-4-OXO-4-(4-CHLOROPHENYL)-2-BUTENOATE 2-[(6-ETHOXY)BENZO[D]-THIAZOLYL]AMMONIUM WITH ANTHELMINTIC AND INSECTICIDAL ACTIVITY | 2016 |
|
RU2657246C2 |
| 2-(4-BROMOPHENYLAMINO)-1-(PIPERAZIN-1-YL)-4-PHENYLBUT-2-EN-1,4-DIONE HYDROCHLORIDE HAVING INSECTICIDAL EFFECT | 2015 |
|
RU2644162C2 |
