FIELD: organic chemistry.
SUBSTANCE: invention relates to the use of biologically active compounds of the class N,1-diaryl-2-methyl-1,2,3,4-thioxo-1,6-tetrahydropyrimidine-4-carboxamides, namely 4-(2-bromophenyl)-1,2,3,4-methyl-N-(5-chlorophenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide. The invention relates to the use of 1,6-dimethyl-N-phenyl-4-(4-fluorophenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide of formula (1):
,
with analgesic activity.
EFFECT: proposed compound exhibits high analgesic activity with low toxicity, which allows it to be used to create an agent with analgesic activity.
1 cl, 2 dwg, 2 tbl, 2 ex
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|
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|
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| METHYL 4-HYDROXY-4-METHYL-6-PHENYL-2-CYANOACETYLHYDRAZONOCYCLOHEXANE-1-CARBOXYLATE EXHIBITING ANALGESIC ACTIVITY | 2010 |
|
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| N-(4'-METHYLBENZOYL)-3,5-DICHLOROANTHRANILIC ACID BUTYLAMIDE EXHIBITING ANTI-INFLAMMATORY AND ANALGETIC ACTIVITY | 2020 |
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RU2753655C1 |
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