SUBSTITUTED BETA-PHENYL-ALPHA-HYDROXYL PROPANOIC ACID, SYNTHESIS METHOD AND USE Russian patent published in 2011 - IPC C07C69/732 A61K31/216 A61K31/36 A61K31/443 A61P9/00 C07C67/08 C07C69/13 C07D317/64 C07D405/12 A61K31/21 A61K31/357 A61K31/4427 

Abstract RU 2421443 C2

FIELD: chemistry.

SUBSTANCE: invention relates to novel compounds of formula (I), where each R1, R2 and R3 is independently selected from a group comprising H, OH, F, Cl, Br, a methoxy group and an ethoxy group; or R1 and R2 together form -OCH2O-, and R3 is selected from a group comprising H, OH, methoxy group, ethoxy group and halogens; R4 denotes OH or o-acetoxybenzoyloxy nicotinoyloxy or iso-nicotinoyloxy; R5 denotes or , and at least one of R1, R2 and R3 is not hydrogen.

EFFECT: method for synthesis of a compound of formula (I) and use of the compound of formula (I) in preparing medicinal agents for preventing or treating cerebrovascular diseases.

17 cl, 14 tbl, 5 dwg, 12 ex

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RU 2 421 443 C2

Authors

Zheng Ksjakhu

Zheng Tsjun'Chzhen

Vang Shiksjang

Zhao Ksinfeng

Dates

2011-06-20Published

2007-05-14Filed