USE OF POROUS FEO NANOSTRUCTURES TO OVERCOME BACTERIA RESISTANCE TO ANTIBIOTICS Russian patent published in 2020 - IPC A61K33/26 B82Y5/00 B82Y40/00 

FIELD: medicine.

SUBSTANCE: group of inventions refers to medicine, namely to potentiating the action of antibiotics, and can be used for treating the wound of the skin and soft tissues infected with multiple-resistant bacteria. That is ensured by using porous Fe₂O₃ (hematite) nanostructures possessing the property of increasing resistance of resistant strains of bacteria to antibiotics characterized by that they have specific surface area of at least 120 m²/g; zeta potential, measured in water at 25 °C, not less than +30 mV, and ratio of mesopore volume to volume of micropores, greater than or equal to 2. Group of inventions also relates to a method of producing said porous Fe₂O₃ (hematite) nanostructures, use thereof as a means of overcoming resistance (resistance) of bacteria to antibiotics and to a product containing said porous Fe₂O₃ nanostructures and at least one antibiotic in the form of a combined preparation.

EFFECT: group of inventions enables the use of low-toxic antibiotics and enables reducing the dose of the antibiotic in treating the wounds infected by multiple resistant bacteria by increasing the resistance of the resistant strains of bacteria to antibiotics.

12 cl, 12 dwg, 1 tbl, 9 ex