ANTIBODIES, SPECIFIC TO HYPERPHOSPHORYLATED TAU-PROTEIN, AND METHODS OF THEIR APPLICATION Russian patent published in 2020 - IPC C07K16/18 A61K39/395 A61P25/14 A61P25/16 A61P25/28 A61P9/00 

Abstract RU 2727911 C2

FIELD: biochemistry.

SUBSTANCE: invention relates to a monoclonal antibody or epitope-binding fragment thereof, capable of immunospecific binding to phosphorylated residue 396 of human tau protein, as well as to composition containing it.

EFFECT: invention provides effective therapeutic approach to taupathy.

3 cl, 34 dwg, 6 tbl, 18 ex

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RU 2 727 911 C2

Authors

Pedersen, Jan, Torleif

Pedersen, Lars, Ostergaard

Dachsel, Justus, Claus, Alfred

Abdur-Rasheed Asuni, Ayodeji

Rosenqvist, Nina

Dates

2020-07-24Published

2016-07-12Filed