Show metadata Hide metadata

(19)

(11)

2 742 691

(13)

(51)

IPC

C07K16/28(2006-01-01)

C07K16/30(2006-01-01)

C07K16/46(2006-01-01)

C12N15/13(2006-01-01)

A61K39/395(2006-01-01)

(21) (22)

Application

2017105120, 2015-08-05

(24)

Start date

2015-08-05

(22)

Actual filing date

2015-08-05

(45)

Published

2021-02-09

(72)

Inventor

Zhukovskij EvgenijLitl MelvinKnakmuss ShtefanRojsh UveEllvanger KristinaFutsek IvitsaVajkhel MikhaelEser MarkusMakalis-Eser Fionnuala

(73)

Holder

Affimed Gmbkh

CD3-BINDING DOMAIN Russian patent published in 2021 - IPC C07K16/28 C07K16/30 C07K16/46 C12N15/13 A61K39/395

Abstract RU 2742691 C2

FIELD: biochemistry.

SUBSTANCE: invention relates to antigen-binding protein for CD3 binding. Also disclosed is a polynucleotide encoding said protein, a pharmaceutical composition containing said antibody. Disclosed is a method of producing said antibody and using said polynucleotide or vector.

EFFECT: invention provides effective treatment of diseases associated with CD3.

11 cl, 1 ex, 1 tbl, 4 dwg

Similar patents RU2742691C2

Title	Year	Author	Number
MULTIVALENT Fv-ANTIBODIES	2016	Ellvanger, Kristina Futsek, Ivitsa Gantke, Ross Myuller, Tomas Rajkovits, Erikh Rejsh, Uve Treder, Martin Vajkhel, Mikhael	RU2785766C2
BISPECIFIC ANTIGEN-BINDING PROTEIN EGFR/CD16	2019	Kluge Michael Tesar Michael Fucek Ivica Ellwanger Kristina Reusch Uwe Damrat Michael Rajkovic Erich Treder Martin	RU2792240C2
VARIANT CD3 BINDING DOMAINS AND THEIR USE IN COMBINATION THERAPY FOR TREATMENT OF DISEASES	2019	Bonvini, Etsio Khuan, Lin Lam, Chia-In Kao Chichili, Gurunad Reddi Alderson, Ralf Froman Mur, Pol A. Dzhonson, Lesli S.	RU2810222C2
CD30XCD16 ANTIBODY COMBINATION FOR THERAPY WITH PD-1 ANTAGONIST	2016	Treder, Martin Rejsh, Uve Marshner, Jens-Piter Knakmuss, Shtefan	RU2761352C2
ANTIBODIES BINDING TO CD3	2019	Freimoser-Grundschober Anne Hofer Thomas Hosse Ralf Moessner Ekkehard Nicolini Valeria G. Umana Pablo Waldhauer Inja Richter Wolfgang Knaupp Alexander Trochanowska Halina	RU2810924C2
TRIFUNCTIONAL ANTIGEN-BINDING MOLECULE	2015	Litl Melvin Zhukovski Evgenij Ezer Markus Vajkhel Majkl Gantke Torsten Rojsh Uve Ellvanger Kristina Le Gall Fabrik	RU2753882C2
ADAM9-BINDING MOLECULES AND THEIR APPLICATION METHODS	2017	Lu, Derik, T. Skrajbner, Dzhuniper, A. Barat, Bkhasvati Didrich, Gundo Dzhonson, Lesli, S. Bonvini, Ezio	RU2783619C2
INDUCIABLE BINDING PROTEINS AND THEIR USE	2017	Baeuerle, Patrick Dubridge, Robert, B. Wesche, Holger Evnin, Luke Guenot, Jeanmarie Panchal, Anand Vinogradova, Maia	RU2800034C2
ANTIBODIES BINDING TO GPRC5D	2019	Fertig Georg Klein Christian Lorenz Stefan Xu Wei Bernasconi Marie-Luise Bujotzek Alexander	RU2797268C2
IMMUNOCYTOKINES AND THEIR USE	2021	Wu Ellen Wu Xiaoyun Wakefield John	RU2818371C1

RU 2 742 691 C2

Authors

Zhukovskij Evgenij

Litl Melvin

Knakmuss Shtefan

Rojsh Uve

Ellvanger Kristina

Futsek Ivitsa

Vajkhel Mikhael

Eser Markus

Makalis-Eser Fionnuala

Dates

2021-02-09—Published

2015-08-05—Filed