VARIABLE DOMAINS OF LIGHT AND HEAVY CHAINS OF MURINE MONOCLONAL ANTIBODIES AGAINST HUMAN ALPHA-DEFENSINS 1-3 (HNP 1-3), ANTIGEN-BINDING FRAGMENTS (FAB) AGAINST HUMAN HNP 1-3, CONTAINING SAID DOMAINS Russian patent published in 2020 - IPC C07K16/18 C12N15/13 A61K39/395 A61P19/02

Abstract RU 2724733 C1

FIELD: biotechnology.

SUBSTANCE: present invention relates to biotechnology and immunology. Variable domains of heavy (VH) and light (VL) chains of mouse monoclonal antibodies against human alpha-defensins 1–3 (HNP 1–3), as well as an antigen-binding fragment of Fab, which selectively bind to alpha-defensins 1-3 (HNP 1–3) of a human being.

EFFECT: present invention can find further application in diagnosing intraarticular infection of large joints.

3 cl, 9 tbl, 5 ex, 9 dwg

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RU 2 724 733 C1

Authors

Varlamov Nikolai Evgenievich

Dates

2020-06-25—Published

2019-09-16—Filed