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IPC

C07K16/24(2006-01-01)

C12N15/00(2006-01-01)

C12P21/08(2006-01-01)

(21) (22)

Application

2018116027, 2018-04-27

(24)

Start date

2018-04-27

(22)

Actual filing date

2018-04-27

(45)

Published

2019-07-16

(72)

Inventor

Solopova Olga NikolaevnaBokov Maksim NikolaevichVarlamov Nikolaj EvgenevichPozdnyakova Lyubov PetrovnaSveshnikov Petr GeorgievichShemchukova Olga BorisovnaZatsepin Sergej SergeevichKlyachko Elena VitalevnaYagudin Timur Anvarovich

(73)

Holder

Otkrytoe Aktsionernoe Obshchestvo Nauchnyj Tsentr Molekulyarnoj Diagnostiki I Lecheniya" Vntsmdl)

VARIABLE DOMAINS OF LIGHT AND HEAVY CHAIN OF THE MOUSE MONOCLONAL ANTIBODY AGAINST INTERFERON ALPHA (IFN-α) HUMAN ANTIGEN BINDING FRAGMENTS (FAb) AGAINST HUMAN IFN-α COMPRISING SAID DOMAINS Russian patent published in 2019 - IPC C07K16/24 C12N15/00 C12P21/08

Abstract RU 2694672 C1

FIELD: biochemistry.

SUBSTANCE: invention relates to the field of biochemistry, in particular to the variable domains of the heavy and light chains of a murine antibody against human interferon alpha (IFN-α). Antigen binding fragment (Fab) is also disclosed that includes these variable domains.

EFFECT: invention makes it possible to effectively communicate with human IFN-α.

3 cl, 7 dwg, 7 tbl, 6 ex

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RU 2 694 672 C1

Authors

Solopova Olga Nikolaevna

Bokov Maksim Nikolaevich

Varlamov Nikolaj Evgenevich

Pozdnyakova Lyubov Petrovna

Sveshnikov Petr Georgievich

Shemchukova Olga Borisovna

Zatsepin Sergej Sergeevich

Klyachko Elena Vitalevna

Yagudin Timur Anvarovich

Dates

2019-07-16—Published

2018-04-27—Filed