FIELD: pharmaceutics.
SUBSTANCE: invention relates to a method for producing antibiotics. Antifungal antibiotics astolides A and B are extracted from mycelium of strain Streptomyces hygroscopicus VKPM Ac2079. Method involves extracting biomass with polar organic solvents with ultrasonic treatment, as well as chromatographic procedure for separation of astolides A and B using reverse-phase sorbents.
EFFECT: method increases output and purity of astolides A and B.
1 cl, 3 ex
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