METHODS FOR DETECTING FOLATE RECEPTOR 1 IN PATIENT SAMPLE Russian patent published in 2021 - IPC G01N33/68 G01N33/577 

Abstract RU 2759410 C2

FIELD: medicine.

SUBSTANCE: method for detecting a human folic acid receptor 1 (hereinafter – FOLR1) in a biological sample is proposed, including the capture of the specified FOLR1 using an immuno-capture reagent bound to solid substrate, elution of FOLR1 from solid substrate, cleavage of eluted FOLR1 and analysis of cleaved FOLR1 by liquid chromatography and mass spectrometry.

EFFECT: invention makes it possible to detect lower levels of FOLR1 in a biological sample.

24 cl, 4 dwg, 8 tbl, 2 ex

Similar patents RU2759410C2

Title Year Author Number
DIAGNOSTIC ANALYSES AND KITS FOR DETECTION OF FOLATE RECEPTOR 1 2018
  • Teste, Netan E.
  • Karrigan, Kristina N.
  • Eb, Olga
  • Tavares, Deniel
  • Vulf, Beni B.
RU2788126C2
ANTIBODIES AGAINST FOLIC ACID RECEPTOR 1, THEIR IMMUNOCONJUGATES AND USE 2011
  • Eb Olga
  • Tavares Deniel
  • Rui Linyun
  • Pejn Dzhillian
  • Goldmakher Viktor S.
RU2740479C2
COMBINATION THERAPY BASED ON T-CELL-ACTIVATING BISPECIFIC ANTIGEN-BINDING MOLECULES AGAINST CD3 AND FOLATE RECEPTOR 1 (FOLR1) AND ANTAGONISTS BINDING TO PD-1 AXIS 2015
  • Klyajn Kristian
  • Karanikas Vaios
  • Shrajner Jens
  • Umana Pablo
  • Tsippelius Alfred
  • Tommen Daniela
RU2753902C2
ANTIBODIES AND ANALYSIS METHODS FOR FOLIC ACID 1 RECEPTOR DETECTION 2014
  • Eb Olga
  • Tavares Deniel
  • Setiadi Dzhulianto
  • Ledd Sherron
  • Karrigan Kristina N.
  • Rui Linyun
RU2725825C2
IMPROVED ANTIGEN-BINDING RECEPTORS 2018
  • Stubenrauch Kay-Gunnar
  • Moessner Ekkehard
  • Klein Christian
  • Darowski Diana
RU2825816C2
TUMOR-TARGETED AGONISTIC CD28-ANTIGEN-BINDING MOLECULES 2019
  • George Guy
  • Hofer Thomas
  • Hosse Ralf
  • Klein Christian
  • Moessner Ekkehard
  • Sam Johannes
  • Umana Pablo
  • Thom Jenny Tosca
  • Gasser Stephan
  • Vallier Jean-Baptiste Pierre
  • Fauti Tanja
RU2808030C2
ANTI-LILRB1 ANTIBODY AND USES THEREOF 2021
  • Choi, Yoon Aa
  • Kim, Han Byul
  • Kang, Shinyoung
  • Kim, Jung A
  • Kim, Heehang
  • Kim, Minsoon
  • Cho, Junhaeng
RU2813373C1
PROCOAGULANT ANTIBODIES 2018
  • Torn, Karina
  • Khansen, Byarne, Gram
  • Jonsen, Laust, Bruun
  • Kharndal, Mikkel, Nors
  • Yan, Chzhizhu
  • Estergaard, Khenrik
  • Grajsen, Per, J
  • Jokhansson, Eva
  • Rash, Morten, Grenbek
  • Chen, Dzyankhe
  • Svensson, Anders
  • Chzhu, Khajsun
  • Chzhou, Zhun
RU2810094C2
HIGH-AFFINITY ANTI-PD-1 AND ANTI-LAG-3 ANTIBODIES AND BISPECIFIC BINDING PROTEINS OBTAINED FROM THEM 2019
  • Wu, Xuan
  • Gong, Shiyong
  • Wu, Chengbin
RU2782381C2
ANTIBODIES AGAINST HLA-G, COMPOSITIONS CONTAINING ANTIBODIES AGAINST HLA-G, AND METHODS OF USE OF ANTIBODIES AGAINST HLA-G 2019
  • Birs, Kortni
  • Korbin, Dzhon
  • Khodzhes, Dug
  • Moesta, Akhim
  • Soros, Vanessa
  • Vidbum, Pol Fredrik
  • Varfild, Dzhozef Robert
RU2810326C2

RU 2 759 410 C2

Authors

Syuj, Rejmond

Kalm-Merdek, Kerri

Dates

2021-11-12Published

2018-09-05Filed