PYRAZOLOPYRIMIDINE COMPOUND AS PI3K INHIBITOR AND USE THEREOF Russian patent published in 2020 - IPC C07D487/04 A61K31/519 A61P35/00 A61P17/00 A61P19/02 A61P11/06 

Abstract RU 2726202 C1

FIELD: chemistry.

SUBSTANCE: invention relates to organic chemistry, specifically to a compound of formula (I):

, where R1 is halogen; R2 is phenyl, where R2 is optionally substituted with R2a from one to five; R2a is selected from H or halogen; R3 is C1-4 alkyl; R4 is H; R5 is cyano; R6 is selected from amino or alkyl, and R7 is selected from H or amino; wherein any hydrogen atom in the compound of formula (I) can be deuterium. Also disclosed is a pharmaceutical composition, use and a method of producing a compound of formula (I).

EFFECT: technical result is obtaining novel compounds which can be used to inhibit lipid kinase activity PI3K.

9 cl, 1 tbl, 7 ex

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RU 2 726 202 C1

Authors

Ye, Baohuan

Dates

2020-07-09Published

2017-10-18Filed