METHOD OF TREATING CENTRAL RETINAL VEIN BRANCH THROMBOSIS COMPLICATED BY MACULAR EDEMA COMBINED WITH NEUROEPITHELIAL DETACHMENT (VERSIONS) Russian patent published in 2020 - IPC A61F9/00 A61F9/08 

Abstract RU 2727876 C1

FIELD: medicine.

SUBSTANCE: group of inventions relates to medicine, namely to ophthalmology. According to the first version of the invention, a threshold laser coagulation is performed in localizing the edema with spreading from the area of arcades to the neuroepithelial detachment (NED). That is followed by optical coherent tomography in angio-mode (OCT-A) according to "En face" protocol for NED zone determination. That is followed by a color photograph of the fundus of Navilas 577s navigation laser using the software. OCT-A digital images are applied and compared with a color photo of the eye ground. NED zone is additionally treated in a selective micropulse mode, for which individual energy parameters are pre-determined by testing the micropulse mode. Three applicants are applied on an intact retina in an upper or lower vascular arcade. Duration of micropulse – 50 mcs, interval between pulses – 1000–2000 mcs, duration of packet – 10 ms, number of pulses in packet – 5, spot diameter – 100 mcm, power – 1.5–1.9 W. After testing short-wave autofluorescence is analyzed and applicants applied with minimum energy parameters are selected. They are placed in preselected patterns of several applicants and placed at 0.25–0.5 of diameter of applicate from each other on a matched photo of eye bottom with OCT data, completely covering area NED. According to the second version of the invention, a threshold laser coagulation is performed in localizing the edema with spreading from the area of arcades to the foveal avascular zone (FAZ). If edema is present in FAZ, laser treatment is performed in selective micropulse mode. Intravitreal 0.05 ml of an angiogenesis inhibitor is pre-introduced. After 2 weeks, OCT is used to evaluate the central thickness of retina (CRT) in fovea. If CRT in fovea is 350 mcm or less, treatment is performed. If CRT in fovea is more than 350 mcm, then 1 month after first introduction of angiogenesis inhibitor, additional intravitreal introduction of 0.05 ml of angiogenesis inhibitor is performed. Two weeks later OCT is performed, and if CRT in fovea is more than 350 mcm, said sequence of actions, including administration of angiogenesis inhibitor and OCT, is repeated until CRV is 350 mcm or less, and treatment is followed.

EFFECT: group of inventions enables restoring NED adherence, eliminating hemorrhages and edema, reducing retinal thickness, eliminating cysts, increasing visual acuity and light sensitivity, as well as reducing or completely eliminating prolonged use of drug preparations and carrying out multiple intraocular injections of angiogenesis inhibitors.

2 cl, 5 ex

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RU 2 727 876 C1

Authors

Volodin Pavel Lvovich

Ivanova Elena Vladimirovna

Kukharskaya Yuliya Igorevna

Dates

2020-07-24Published

2019-12-12Filed