ANTIBODIES SPECIFIC TO HYPERPHOSPHORYLATED TAU-PROTEIN AND THEIR APPLICATION METHODS Russian patent published in 2021 - IPC C07K16/18 

Abstract RU 2760875 C1

FIELD: biochemistry.

SUBSTANCE: invention relates to the field of biochemistry, in particular to a monoclonal antibody that specifically binds to a pathogenic hyperphosphorylated tau-protein. The application of the specified antibody for the treatment of taupathy and for the treatment of Alzheimer’s disease is also disclosed.

EFFECT: invention has the capability of the effective treatment of diseases associated with a tau-protein.

7 cl, 11 ex, 6 tbl, 26 dwg

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RU 2 760 875 C1

Authors

Pedersen, Yan, Torlejf

Kyaergaard, Kristian

Pedersen, Lars, Ostergaard

Asuni, Abdur-Rashid

Rozenkvist, Nina, Khelen

Dechsel, Yustus, Klaus, Alfred

Dzhukhl, Karsten

Tagmose, Lena

Marigo, Mauro

Jensen, Tomas

Kristensen, Soren

David, Laurent

Folbrakht, Kristian

Khelbo, Loun

Dates

2021-12-01Published

2017-07-07Filed