FIELD: medicine; oncology.
SUBSTANCE: group of inventions can be used for treating a brain tumor. Method of treating a brain tumor involves administering an effective amount of Plinabulin to a subject, wherein said cerebral tumor is a metastatic brain tumor, anaplastic astrocytoma, glioblastoma multiforme, pediatric ependyma and subependyma oligodendroglioma. Group of inventions also relates to inhibition of proliferation, inducing apoptosis of brain tumor cells, as well as to inhibition of brain tumor progression.
EFFECT: use of the given group of inventions enables higher survival rate of the subject with transforming growth factor-induced gliomas, which expressed mutant by G12D KRAS.
24 cl, 4 dwg, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF TREATING CANCER ASSOCIATED WITH A RAS MUTATION | 2016 |
|
RU2736045C2 |
| DEOXYDERIVATIVES OF CYTIDINE OR URIDINE FOR USE IN THE TREATMENT OF CANCER | 2020 |
|
RU2797489C2 |
| METHODS OF TREATING CANCER DISEASES AND TUMORS USING PDE1 INHIBITORS | 2019 |
|
RU2811918C2 |
| USE OF INHIBITORS OF IMMUNE CONTROL POINTS IN NEW GROWTHS OF CENTRAL NERVOUS SYSTEM | 2015 |
|
RU2726996C1 |
| USE OF THE PLINABULIN IN COMBINATION WITH THE IMMUNE RESPONSE CONTROL POINT INHIBITORS | 2016 |
|
RU2723021C2 |
| ONCOLYTIC HERPES SIMPLEX VIRUSES TYPE 1 FOR TREATING BRAIN TUMOURS | 2021 |
|
RU2824514C1 |
| CEREBRAL CANCER TREATMENT WITH ONCOLYTIC ADENOVIRUS | 2014 |
|
RU2689553C2 |
| PHARMACEUTICAL COMPOUNDS | 2020 |
|
RU2826182C1 |
| CANNABINOIDS IN COMBINATION WITH NON-CANNABINOID CHEMOTHERAPEUTIC AGENTS (FOR INSTANCE, SERMS OR ALKYLATING AGENTS) | 2009 |
|
RU2543034C2 |
| TREATMENT OF CANCER BY COMBINATION OF PLINABULIN AND TAXANE | 2013 |
|
RU2662298C2 |
