FIELD: medicine; oncology.
SUBSTANCE: group of inventions can be used for treating a brain tumor. Method of treating a brain tumor involves administering an effective amount of Plinabulin to a subject, wherein said cerebral tumor is a metastatic brain tumor, anaplastic astrocytoma, glioblastoma multiforme, pediatric ependyma and subependyma oligodendroglioma. Group of inventions also relates to inhibition of proliferation, inducing apoptosis of brain tumor cells, as well as to inhibition of brain tumor progression.
EFFECT: use of the given group of inventions enables higher survival rate of the subject with transforming growth factor-induced gliomas, which expressed mutant by G12D KRAS.
24 cl, 4 dwg, 2 ex
Title |
Year |
Author |
Number |
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2016 |
|
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2020 |
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|
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2019 |
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|
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2016 |
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|
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2021 |
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|
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2014 |
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- Konrad Charlz
|
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2009 |
- Velasko Dies Gil'Ermo
- Gusman Pastor Manuehl'
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- Torres Sofija
|
RU2543034C2 |
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2013 |
|
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2019 |
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|
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