FIELD: medicine; oncology.
SUBSTANCE: group of inventions discloses a method of treating glioma, including administering a pharmaceutically acceptable amount of a PDE1 inhibitor to a subject in need thereof, where the PDE1 inhibitor is selected from any of the following compounds in free form or in the form of a pharmaceutically acceptable salt. A method of inhibiting cytokine release syndrome is also disclosed.
![](/patent/RU2811918C2/i/00000024.png)
EFFECT: technical result is the implementation of the purpose of the claimed methods.
6 cl, 5 tbl, 7 dwg, 3 ex
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