FIELD: medicine.
SUBSTANCE: group of inventions can be used to produce a medicinal agent based on a liposome composition for treating a condition associated with inflammation. Liposome contains a lipid ingredient and encapsulates the bisphosphonate. Liposome has weight ratio of said bisphosphonate to lipid ingredient from 1:5 to 1:8. Lipid ingredient contains distearoyl phosphatidyl choline (DSPC), distearoyl phosphatidyl glycerol (DSPG) and cholesterol in molar ratio of 3:1:2. Liposome has compressibility value less than 0.70 ml/g. Invention also discloses a liposome, a composition of liposomes and use of a formulation for preparing a medicinal agent.
EFFECT: group of inventions enables to obtain a homogeneous and stable liposomal composition for treating a condition associated with inflammation.
15 cl, 6 tbl, 5 dwg, 4 ex
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