FIELD: biotechnology.
SUBSTANCE: described is a group of inventions comprising a vaccine composition for inducing a protective immune response to a virus and a method of preventing a viral infection involving administering a vaccine composition, where the virus is selected from a group consisting of respiratory syncytial virus (RSV), rabies virus, Ebola virus and influenza virus. In one version of the invention, the vaccine composition contains a nanoparticle containing a core which contains a non-ionic detergent, and a viral glycoprotein associated with the nucleus, wherein the viral glycoprotein is selected from a group consisting of F-glycoprotein RSV, Ebola virus glycoprotein, rabies virus G-protein, influenza virus haemagglutinin (HA) protein, influenza virus neuraminidase (NA) protein and combinations thereof.
EFFECT: invention extends the range of agents for inducing an immune response to a virus.
23 cl, 50 dwg, 1 tbl, 25 ex
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Authors
Dates
2020-08-24—Published
2016-09-06—Filed