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(19)

(11)

2 788 403

(13)

(51)

IPC

C07K14/05(2006-01-01)

C07K14/08(2006-01-01)

C07K19/00(2006-01-01)

C12N15/09(2006-01-01)

A61K39/12(2006-01-01)

A61P31/14(2006-01-01)

(21) (22)

Application

2020115606, 2016-12-09

(24)

Start date

2016-12-09

(22)

Actual filing date

2016-12-09

(45)

Published

2023-01-19

(72)

Inventor

Che, YeDormitzer, Philip RalphGribenko, Alexey VyacheslavovichHandke, Luke DavidPrasad, Avvari KrishnaQiu, XiayangRuppen, Mark EdwardSong, XiSwanson, Kena AnneKodali, SrinivasXu, XinEfferen, Kariann SweeneyCai, PingTompkins, Kristin RachaelNunez, Lorna Del Pilar

(73)

Holder

Pfizer Inc.

F RSV PROTEIN MUTANTS Russian patent published in 2023 - IPC C07K14/05 C07K14/08 C07K19/00 C12N15/09 A61K39/12 A61P31/14

Abstract RU 2788403 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to the field of biotechnology, in particular to F respiratory syncytial virus (hereinafter – RSV) protein mutants, to vaccines against RSV, containing F RSV protein mutants, as well as to a method for the prevention of RSV infection in a human by administration of the above-mentioned vaccine.

EFFECT: mutants of F protein, according to the present invention, allow for obtainment of effective vaccines against RSV.

18 cl, 9 dwg, 23 tbl, 11 ex

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RU 2 788 403 C2

Authors

Che, Ye

Dormitzer, Philip Ralph

Gribenko, Alexey Vyacheslavovich

Handke, Luke David

Prasad, Avvari Krishna

Qiu, Xiayang

Ruppen, Mark Edward

Song, Xi

Swanson, Kena Anne

Kodali, Srinivas

Xu, Xin

Efferen, Kariann Sweeney

Cai, Ping

Tompkins, Kristin Rachael

Nunez, Lorna Del Pilar

Dates

2023-01-19—Published

2016-12-09—Filed