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(19)

(11)

2 761 631

(13)

(51)

IPC

C07K14/135(2006-01-01)

C12N15/11(2006-01-01)

C12N15/63(2006-01-01)

C12N5/10(2006-01-01)

A61K35/76(2015-01-01)

A61P31/12(2006-01-01)

A61P37/04(2006-01-01)

(21) (22)

Application

2015142981, 2014-03-13

(24)

Start date

2014-03-13

(22)

Actual filing date

2014-03-13

(45)

Published

2021-12-13

(72)

Inventor

Kvong Piter D.Grekhem Barni S.Maklellan Dzhejson S.Dzhojs Majkl GordonKanekijo MasaruChzhan BaoshanBojington DzheffriDzhordzhiv Ivelin StefanovPansera MariSoto SinkeSrivatsan SandzhajStyuart-Dzhons GijomChen LejChen ManChuan Gvo-YuGorman DzhejsonOfek DzhiladSastri MallikaYang JongpingChzhou Tuntsin

(73)

Holder

Dze Yunajted Stejts Of Amerika, Es Reprezented Baj Dze Sekreteri, Department Of Khelt End Khyuman Servisiz

RSV PROTEINS IN PRE-CONFLUENCE CONFORMATION AND USE THEREOF Russian patent published in 2021 - IPC C07K14/135 C12N15/11 C12N15/63 C12N5/10 A61K35/76 A61P31/12 A61P37/04

Abstract RU 2761631 C2

FIELD: biotechnology.

SUBSTANCE: invention refers to producing an immunogen for inducing an immune response on F RSV protein and can be used in medicine.

EFFECT: obtained immunogen containing protein F1 and ectodomain F2 of protein F RSV, stabilized in conformation preceding conformation, can be used for effective prevention of RSV infection in an individual and detection of antibodies to protein F RSV.

46 cl, 84 dwg, 25 tbl, 15 ex

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RU 2 761 631 C2

Authors

Kvong Piter D.

Grekhem Barni S.

Maklellan Dzhejson S.

Dzhojs Majkl Gordon

Kanekijo Masaru

Chzhan Baoshan

Bojington Dzheffri

Dzhordzhiv Ivelin Stefanov

Pansera Mari

Soto Sinke

Srivatsan Sandzhaj

Styuart-Dzhons Gijom

Chen Lej

Chen Man

Chuan Gvo-Yu

Gorman Dzhejson

Ofek Dzhilad

Sastri Mallika

Yang Jongping

Chzhou Tuntsin

Dates

2021-12-13—Published

2014-03-13—Filed