FIELD: pharmaceutics.
SUBSTANCE: invention relates to chemical and pharmaceutical industry, specifically a method of producing lenalidomide intermediate of formula (10) by reacting 3-nitrophthalaldehyde with 3-amino-2,6-piperidinedion in the presence of a reducing agent and an organic acid in a medium of a chlorinated organic solvent, and further conversion of the intermediate into lenalidomide by reduction of the nitro group.
(10).
EFFECT: present method is environmentally friendly, safe and provides for use of readily available raw material.
10 cl, 3 dwg
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