ARYLALKYLAMINE COMPOUNDS FOR USE IN PREVENTING OR TREATING CANCER Russian patent published in 2020 - IPC A61K31/137 A61K31/33 A61K31/343 A61P43/00 A61P35/00 A61P35/02 

FIELD: medicine; pharmaceuticals.

SUBSTANCE: invention relates to a method for preventing or treating cancer or cancer metastasis in a mammal by a compound of general formula II or its pharmaceutically acceptable salt as the sole biologically active substance, which is a compound-amplifier of catecholaminergic activity, which increases the release of the catecholamine neurotransmitter from the catecholaminergic neurons in the central nervous system, the daily dose of less than 0.01 mg per kg of body weight, where in formula II Q is a group, consisting of a substituted or unsubstituted aromatic six-membered ring, and where, if Q is substituted, the substitute is selected from a group consisting of hydrogen, hydroxyl, C_1-4-alkyl, C_1-4-alkoxy and halogen, preferably Q is substituted with one or two substituents or has no substitutes, R₁ is C_1-5-alkyl, preferably is methyl, ethyl or propyl, R₂ is C_1-4-alkyl, C_2-4-alkenyl or C_2-4-alkynyl, R₃ is hydrogen, methyl or ethyl.

EFFECT: technical result is a novel method of preventing or treating cancer by a compound of formula (II), which can be used in medicine.

15 cl, 14 dwg, 4 tbl, 5 ex