FIELD: biochemistry; molecular biology; biotechnology.
SUBSTANCE: invention relates to a reagent based on alpha-fetoprotein immobilized on the surface of solid microparticles of polyethylene terephthalate (PET microparticles), as well as to a method for site-specific covalent immobilisation of alpha-fetoprotein on the surface of functionalised PET microparticles per a glycoside protein fragment.
EFFECT: disclosed is a method of producing alpha-fetoprotein immobilized on PET microparticles.
2 cl, 11 ex, 1 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PRODUCING MODIFIED COMBINATORIAL DNA LIBRARIES BY SOLID-PHASE PRIMER EXTENSION REACTION ON PET MICROPARTICLES | 2018 |
|
RU2734941C2 |
| METHOD OF ALPHA-FETOPROTEIN PREPARATION PREPARING | 1998 |
|
RU2123009C1 |
| THERMAL DISSOCIATION METHOD FOR SELECTION OF DNA-APTAMERS | 2019 |
|
RU2723373C1 |
| METHOD FOR PRODUCING ACTIVE FRAGMENT OF HUMAN ALPHA-FETOPROTEIN | 2010 |
|
RU2448116C2 |
| CONJUGATE OF BIOLOGICALLY ACTIVE SUBSTANCES WITH $$$-FETOPROTEIN SHOWING THE SELECTIVE ACTION WITH RESPECT TO CANCER TUMORS, METHOD OF THEIR PREPARING (VARIANTS) AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF | 1996 |
|
RU2071351C1 |
| METHOD OF OBTAINING RADIOLABELLED WITH RADIONUCLIDES ALPHA-FETOPROTEIN IODINE AND METHOD OF ITS IMPLEMENTATION FOR DIAGNOSTICS OF MALIGNANT TUMORS | 2009 |
|
RU2404812C1 |
| METHOD FOR PREPARING PREPARATION DRY ALPHA-FETOPROTEIN | 2005 |
|
RU2283131C1 |
| METHOD FOR PREPARING ALPHA-FETOPROTEIN PREPARATION TABLET | 2005 |
|
RU2319479C2 |
| METHOD FOR PRODUCTION OF ALPHA-FETOPROTEIN | 2006 |
|
RU2308286C1 |
| METHOD OF PRODUCING CONJUGATE OF FRAGMENT OF HUMAN ALPHA-FETOPROTEIN WITH CIPROFLOXACIN | 2010 |
|
RU2431639C1 |
