FIELD: medicine.
SUBSTANCE: invention refers to medicine, particularly to pathomorphology, obstetrics and gynecology. What is presented is a method for assessing endometrial receptivity in the period of the "implantation window" for correcting the tactics of high-technology reproductive technologies (HRT) in females with primary endometriosis-associated infertility. On 20th-22nd day of the menstrual cycle, endometrial pipelle biopsy is used to determine expression of PTEN and p53, followed by calculating a prognostic index (PI) by formula PI = X1×-0.54+0.233×X2-0.165×X3+29.2. If PI is more than 0, the endometrial is considered to be ready for successful implantation of the embryo and possibility of directing the woman to the HRT program. If PI is less than 0, high risk of reproductive failures in HRT programs is predicted.
EFFECT: invention enables high-probability determination of endometrial susceptibility to blastocyst implantation during the "implantation window" in females with primary infertility caused by endometriosis.
1 cl, 3 ex
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