FIELD: biotechnology.
SUBSTANCE: described is a method of treating an infectious disease in a subject, a method for modifying an immune response to an infectious agent in a subject and a method of activating T-cell responses to an infectious agent in a subject. Above methods are implemented with participation of an antibody or its antigen-binding part containing: Heavy chain CDR1 containing amino acids, having sequence given in SEQ ID NO: 15–21; CDR2 heavy chain containing amino acids having a sequence given in SEQ ID NO: 22–28; CDR3 heavy chain containing amino acids, having sequence given in SEQ ID NO: 29–35; CDR1 light chain containing amino acids having the sequence given in SEQ ID NO: 36–42; Light chain CDR2 containing amino acids, having sequence given in SEQ ID NO: 43–49; and light chain CDR3 containing amino acids having the sequence given in SEQ ID NO: 50–56.
EFFECT: invention extends the range of products for treating infectious diseases.
19 cl, 54 dwg, 7 tbl, 24 ex
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Authors
Dates
2020-09-24—Published
2016-08-18—Filed