METHODS OF DETERMINING RENAL FUNCTION Russian patent published in 2020 - IPC A61K49/00 C07D241/20 A61P13/12 

Abstract RU 2734776 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to a method of determining glomerular filtration rate (GFR) in a patient in need thereof. Method comprises administering to said patient a compound of formula I or a pharmaceutically acceptable salt thereof, measuring the concentration of the compound of formula I in said patient during the measurement time interval and determining the GFR in said patient; where formula I compound is:

and where said patient in need thereof has at least CKD stage 1.

EFFECT: invention provides a wider range of means for determining glomerular filtration rate, as well as helps diagnose patients with CKD by increasing accuracy.

13 cl, 8 tbl, 19 ex, 30 dwg

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RU 2 734 776 C1

Authors

Rajagopalan, Raghavan

Dorshow, Richard B.

Neumann, William L.

Rogers, Thomas E.

Dates

2020-10-23Published

2018-10-26Filed