AEROSOL FOR INHALATIONS IN OBSTRUCTIVE BRONCHITIS Russian patent published in 2020 - IPC A61K31/167 A61K31/327 A61K9/12 A61P11/10 

FIELD: medicine; pharmacology.

SUBSTANCE: invention refers to pharmacology, pharmacy, namely to an inhalation aerosol in obstructive bronchitis intended for expectoration of pus and mucus in order to facilitate breathing and to eliminate hypoxia during resuscitation. Aerosol contains drinking soda, medicines and distilled water at temperature higher than 40 °C, provides microparticles sizes in range of 0.5–2 mcm by means of liquid spraying or disperse spraying with the help of ultrasonic, compression and jet inhalers and nebulisers, characterized by that the medicines used are hydrogen peroxide and lidocaine hydrochloride, wherein components are contained in following ratio (wt. %): sodium bicarbonate - 1.2; hydrogen peroxide - 0.3–0.5; lidocaine hydrochloride - 0.5; distilled water - balance, at pH 8.5, osmotic activity 280–300 mOsm/l of water and local temperature +41 – +55 °C.

EFFECT: invention provides the urgent dissolution of thick pus, thick mucus with blood veins, improved expectoration, respiratory relief, bronchial lumen enlarging, increased content of oxygen in bronchi without local irritant action, without amplification of obstructive bronchitis symptoms, without developing pneumonia, acidosis, alcoholic intoxication and bronchial spasm in resuscitation patients.

1 cl