ARTIFICIAL SPUTUM FOR MODELING RESPIRATORY OBSTRUCTION IN COVID-19 Russian patent published in 2021 - IPC G01N33/15 

FIELD: medicine; pulmonology; pharmacology; pharmacy; biotechnology; biochemistry; physical and colloidal chemistry

SUBSTANCE: artificial sputum is disclosed intended for filling the respiratory tract of an isolated lung and depriving it of airiness for urgent use as a biological model for screening expectorants and foaming agents at the following ratio (wt.%): potato starch is 4.4-22.0; gelatin is 2.2-11.0; sodium chloride is 0.9; blood of an agricultural animal diluted with distilled water in a ratio of 1:1-5.0; distilled water is the rest, at a pH of 7.0-7.4, osmotic activity of 280-300 mOsm/l of water and a temperature of +37°С.

EFFECT: invention provides urgent filling of the respiratory tract up to the elimination of airiness and drowning of the isolated lung in water, the possibility of using the lung as a biological model for screening expectorant and oxygen foaming drugs when they are inhaled without burn and frostbite damage to the lung tissues, without the development of cold spasm of the bronchi and without infection of the performers.

1 cl, 7 ex