FIELD: medicine; embryology; immunology.
SUBSTANCE: group of inventions can be used to determine mammalian fertility. That is ensured by using CD146 (sCD146) soluble protein present in embryo culture medium as biomarker of implantation of said embryo in uterus of mammal. Group of inventions relates to a method of selecting an embryo produced by in vitro fertilization (IVF), for implantation into a uterus of a mammal, as well as to a method for increasing pregnancy probability in vitro in a mammal and a method of stimulating pregnancy in a mammal.
EFFECT: using the given group of inventions makes it possible to increase probability of pregnancy during fertilization in vitro in a mammal when determining threshold value of concentration sCD146 making 1164 pg per ml supernate of a medium for embryo cultivation.
13 cl, 6 dwg, 1 tbl
Title |
Year |
Author |
Number |
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2016 |
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2011 |
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|
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